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Your opportunity to help give men more good years with their families

Hormone therapy is often offered as the first treatment following a man’s diagnosis of advanced prostate cancer; however, for many, it doesn’t always last long and their cancer can start spreading again. Doctors will often wait for this stage of a man’s treatment journey to offer chemotherapy due to its potential side effects.

Men with advanced prostate cancer need personalised treatments tailored to their circumstances, and they need them now.

By making a donation, you can help us make sure no man's life is cut short.

Make a donation

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Professor Simon Crabb and Dr Sarah Chamberlain - two of the expert leads of INTENSIFY

INTENSIFYing treatment for men with advanced prostate cancer

We’re funding the INTENSIFY research trial to test whether adding chemotherapy earlier in a man’s treatment journey - when hormone therapy is still working - could keep them alive for longer. 

The researchers behind INTENSIFY are finding a way to use PSA blood tests to identify men whose hormone therapy is likely to stop working and who could benefit from the addition of chemotherapy. 

As well as testing whether intensified treatment can improve a man’s outcome, the research team is also trialling a new genetic test to spot men who might not respond well to chemotherapy, so they can be spared the potential side effects of this treatment.

By using tests already availablesuch as PSA tests - to identify when hormone therapy isn’t working well enough, this trial could deliver immediate change for men with advanced prostate cancer.

Read more about INTENSIFY.

You can give men the personalised treatment that gives them the best possible outcome.

Make a donation

Everything seems to be going well. I’m tired, but that’s the only side effect I’ve got. And if I keep busy, I can work through it. It hasn’t kept me out of the garden.
Bob Webster

Bob's story

When Bob Webster, 77, was diagnosed with advanced prostate cancer in 2023, he immediately started hormone therapy.

Unusually, his doctors intensified his treatment by adding a course of chemotherapy shortly after. This combination has been working well for Bob, and the slight side effects he’s experienced haven’t stopped him from taking care of his garden and vegetable patch.

The pairing of hormone therapy and chemotherapy has allowed Bob to continue doing the things he loves, but it’s rare for men to be offered this treatment combination. 

INTENSIFY could finally change this. If successful, this research would confirm that this treatment combination can keep some men - like Bob - alive for longer and give men with advanced prostate cancer hope for more good years to spend doing the things they love.

By funding INTENSIFY, you could give men with advanced prostate cancer more years with their loved ones.

Make a donation

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Bob, his wife Julie, and their dog Ollie