Pain and advanced prostate cancer

Some men with advanced prostate cancer will experience pain. Pain can feel different from one person to another, and you may experience different levels of pain at different times. 

Pain is more common in men whose cancer has spread to their bones. Although, even if the cancer has spread to several places in your body, you might not feel pain in all of these places. With the right treatment and management, pain can usually be relieved or reduced. 

Download or order Managing pain in advanced prostate cancer fact sheet

What causes the pain?

We feel pain when our bones, muscles, organs, nerves or other parts of our bodies are damaged or irritated. Cancer which has spread into these areas might cause pain. 

Some treatments for prostate cancer can also cause pain. Pain can also be caused by problems not linked to the cancer, such as an infection.

Some people dismiss pain and put it down to other causes, such as simply getting older. But if you have pain, you should always get it checked out by a doctor to find out the cause.

 

Types of pain 

If prostate cancer spreads to the bone, it can damage or weaken it and may cause pain. Prostate cancer can spread to any area of bone around the body. It most commonly spreads to the spine. Pain in these areas can sometimes make it painful to walk and move around. The pain might remain in only one area, or spread to several parts of your body over time.

Bone pain is a very specific feeling. Some men describe it as feeling similar to a toothache but in the bones, or like a dull aching or stabbing. It can get worse when you move and can make the area tender to touch. Each man’s experience of bone pain will be different. The pain may be constant or it might come and go. How bad it is can also depend on where the affected bone is.

Nerve pain is caused by damage to a nerve, for example if the cancer presses on a nerve. The outer layers of bones contain nerves, and neuropathic pain can be a part of bone pain. The pain can come and go and people have described it as a shooting, stabbing, burning or tingling pain. For some people, the damaged area feels numb.

Sometimes damage to one part of your body is felt as pain in a different area. This is called referred or reflective pain. For example, cancer pressing on a nerve in the spine could be felt as a pain in the chest, arms or legs.

You may have a type of nerve pain called sciatica. Sciatica is caused by damage to one or more of the nerves that start in the spine and run down through the legs. People feel sciatica as pain, numbness, weakness, pins and needles or tingling in the lower back, buttocks, legs or feet. Sciatica can sometimes make it difficult to move the affected leg.

Sciatica is more likely to be caused by something other than your prostate cancer. But it’s still a good idea to have it checked out by your doctor or nurse.

If the cancer spreads to the lymph nodes it could lead to a condition called lymphoedema – caused by a blockage in the lymphatic system. But this isn’t very common. The lymphatic system is part of your body’s immune system, carrying fluid called lymph around your body. If it is blocked, the fluid can build up and cause swelling (lymphoedema).

Lymphoedema in prostate cancer usually affects the legs, but it can affect other areas, including the penis or scrotum (the skin around your testicles). Some men notice that the part of their body that is affected aches or feels tight or heavy. Prostate cancer itself can cause the blockage, and so can some treatments, such as surgery or radiotherapy. Lymphoedema can occur months or even years after treatment.

If you think you might have lymphoedema, speak to your doctor or nurse.

There might be a local lymphoedema service that your doctor or nurse can refer you to. Lymphoedema can cause discomfort or pain but there are treatments and things you can do yourself to help manage it, including eating a well-balanced diet.

You might get pain if you have metastatic spinal cord compression (MSCC). This happens when cancer cells grow in or near to the spine and press on the spinal cord.

MSCC isn’t common but it is serious. You need to be aware of the risk if you have advanced prostate cancer. Read more about metastatic spinal cord compression and what to look out for.

How much pain will I have?

Some men with advanced prostate cancer have no pain. Others may have mild pain or pain that affects their daily life. 

Everyone’s experience of pain is different, so it’s hard to know how it will affect you. How much pain you have will depend on several things, including: 

  • where the pain is
  • what’s causing the pain
  • how soon your doctor or nurse can help you manage the pain
  • finding the right pain relief for you
  • taking the right amount of pain-relieving drugs at the right times
  • how tired you feel
  • how well you feel in general
  • if you feel anxious
  • if you feel depressed.

What should I do if I have pain?

Tell your doctor or nurse about any pain as soon as you can. The sooner you get help, the easier it is to control. You don’t have to put up with pain. With the right treatment, it can usually be managed.

Keeping a pain diary can help. Write down when you have pain, how strong it is, where it is, and what medicines you take. This can help your doctor or nurse find the best way to treat it.

Download our pain diary here

Your doctor or nurse will ask you questions about your pain to try to get as much information about it as possible. This will help them work out the best treatment for you. They might ask you the following questions.

  • Where is your pain? Does it stay in the same place or does it move around?
  • How bad is it?
  • What does it feel like? For example, is it a stabbing pain, or a dull ache?
  • When did the pain start? How often do you get it? How long does it last?
  • Does it wake you at night?
  • Does anything help?
  • Have you tried any pain-relieving medicines? Did they help?
  • Does anything make it worse?
  • How does your pain make you feel? For example, do you feel anxious or depressed? Does this affect the pain?
  • How does the pain affect your daily life?
  • Have you noticed any other symptoms associated with the pain? For example, numbness or weakness?

Who can help manage my pain?

Various health professionals can help you manage your pain, depending on the cause and management of your pain. It might be your GP, hospital doctor or nurse, or health professionals in the community. They might be part of a pain team or a palliative care team. You may see some of the following health professionals.

  • A palliative care doctor or nurse who can treat and manage physical symptoms, including pain, as well as offer psychological and spiritual support. They work with other health professionals to co-ordinate your care and can refer you to local services
  • Specialist cancer nurses who provide advice about how to manage symptoms and side effects, as well as the different types of pain treatment
  • A clinical psychologist who may be able to help you deal with your pain
  • A physiotherapist who can show you how to move about without making the pain worse. They might also suggest gentle exercises that will help
  • An occupational therapist (OT) who can help you get the right equipment in your house to be more comfortable and move about more easily
  • A complementary therapist who might be able to help you feel more relaxed or help you deal with the side effects of pain or pain-relieving drugs

Your doctor might also make an appointment for you at a pain clinic run by health professionals who specialise in treating pain. Ask your doctor or nurse about what pain services are available, and how you can be referred to them.

What treatment can I have?

There are different ways to treat pain. The best treatment for you depends on what’s causing the pain, your general health, how you're feeling emotionally and your daily activities. By using a combination of treatments to suit your needs, pain from cancer can usually be managed well.

Treatment to manage your pain

You might need treatment for the pain itself, such as:

Read more about treatments to manage pain in advanced prostate cancer.

There are other things that may also help with pain, including:

Treatments to control your cancer 

Pain might be a sign that your prostate cancer treatment is not working as well as it was. A different treatment for your cancer may help the pain. Possible treatments include:

  • Hormone therapy: This aims to shrinks or slows the growth and spread of the cancer. This can prevent of relieve your pain. 
  • Steroids: These may be offered if treatments, such as hormone therapy, are no longer working.
  • Chemotherapy: This aims to shrink the cancer and slow down its growth. This can help with symptoms, including pain.
  • A type of radiotherapy called radium-223: This can delay some symptoms, such as bone fractures, and can help to reduce bone pain.

Read more about treatments to manage pain in advanced prostate cancer. 

Dealing with pain and prostate cancer

Until your pain is under control it may be very difficult to think clearly or believe that the pain will go away.

Coping with any type of pain, whether it's constant or it comes and goes, can be tiring and frightening. Pain can affect your daily activities, your relationships with other people, your sleep, and your ability to enjoy life.

Pain can also affect your thoughts and feelings. There’s no right way that you’re supposed to feel and everyone reacts in their own way.

You might feel scared, worried, stressed, helpless or even angry. Some people with pain say they feel angry or depressed. And some men worry that their pain is a sign that their cancer is getting worse.

Visit our wellbeing hub for information to help support you in looking after your emotional, mental, and physical wellbeing. 

Your feelings can also affect your pain – anxiety can make it worse, and feeling low can make you more aware of your pain. It might be useful to get some extra help if you’re feeling down, for example by talking to a counsellor.

Tiredness can also be a big problem if you’re living with pain. If you’re feeling very tired, speak to your GP or your doctor or nurse at the hospital. They can give you advice and support. Read more about extreme tiredness (fatigue) or find out how our Specialist Nurses can help you with your fatigue.

There are things you can do to help yourself and people who can help.

Families and close friends often say it can be difficult to watch a loved one in pain. They may find it hard to know how to help and may also need emotional or practical support. If you’re a partner, family member or friend of someone with prostate cancer, you may like to read our information for people who are close to someone with prostate cancer.

It may be useful to speak to your nurse, doctor, GP or someone else in your medical team. They can explain your diagnosis, the cause of your pain, possible treatment options, and any side effects. They can listen to your concerns, and put you in touch with other people who can help.

Make sure you and your family know who to contact if your pain suddenly gets worse. If you’re unsure, ask your doctor or nurse and keep the instructions somewhere close.

If you’re in a lot of pain, it can be difficult to think straight, so it may help to bring someone to the hospital with you to help talk to the doctor or nurse and to make notes for you.

You may be able to get support from your local hospice or community palliative care team.

Hospices don’t just provide care for people at the end of their life. They provide a range of services, including treatment to manage pain. They can also offer emotional and spiritual support, practical and financial advice, and support for families.

Some hospices provide day centres with services such as complementary therapy. Or you might be able to stay at the hospice for a short time while they get your pain under control. 

The community palliative care team can usually come and visit you at home if you prefer. Both teams will have doctors and nurses who can adjust the dose of your pain-relieving drugs and help get your pain under control.

Your GP, doctor or nurse at the hospital, or district nurse can refer you to a hospice service or community palliative care team. They will continue to work closely with these teams to support you. You can find out more about these services from Hospice UK, Macmillan Cancer Support and Marie Curie.

Read more about thinking and planning ahead, including hospice support.

Counsellors are trained to listen and can help you find your own ways to deal with things. Many hospitals have counsellors or psychologists who specialise in helping people with cancer – ask your doctor or nurse at the hospital if this is available.

You can also refer yourself for counselling on the NHS website, or you could see a private counsellor. To find out more, contact the British Association for Counselling & Psychotherapy.

References and reviewers

Updated: March 2026 | Due for Review: March 2029

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  • Vanessa Basketter, Urology Nurse Specialist, University Hospital Southampton
  • Maggie Bingle, Prostate Cancer Clinical Nurse Specialist, East Suffolk and North Essex NHS Foundation Trust
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