Researcher - Dr Luke Gaughan
Institution - Newcastle University
Grant award - £99,862.32
Reference – S14-007
The androgen receptor is very important for prostate cancer growth and spread. This project looks at understanding how different forms of the androgen receptor are regulated in advanced prostate cancer.
Variant androgen receptors are commonly found in the cells of men with advanced prostate cancer and their presence allows the cancer cells to grow even in the presence of treatment. These altered receptors are therefore a major problem for men with advanced disease.
Understanding how the androgen receptor is regulated during the progression of advanced prostate cancer is important for the identification of new, targeted treatments that could provide a better long-term solution for men with advanced disease.