Researcher - Dr Dow-Mu Koh
Institution – Royal Marsden Hospital
Grant award - £221,580
Reference – PG14-016-TR2
In a nutshell
The researchers are looking at whether an imaging technique called whole body diffusion weighted imaging (WBDWI). The advantage of WBDWI is that it provides a global view of the body. This project looks at whether WBDWI can be used as a reliable marker of how well patients with advanced prostate cancer, who have been treated with a drug called olaparib, are responding to treatment.
Why we funded it
Prostate cancer often spreads to the bones, and assessment of metastatic bone disease with standard imaging is unreliable. WBDWI is a promising imaging technique for assessing how bone metastases are responding to treatment. The researchers expect that men who respond well to olaparib treatment will show an improvement in the parameters measured by WBDWI. They hope to identify the patients who will benefit most from the treatment, as well as measure how well the treatment is working. WBDWI can help to terminate ineffective treatment and allow, the switch to a new therapy, so that prostate cancer patients may have a good quality of life for as long as possible.