Samples - Major Awards Existing Trials: New Answers

Open for applications - Apply now!

Over the past decade, many clinical trials have and are taking place internationally which are changing the way prostate cancer is diagnosed and treated. Many of these trials have not only produced practice-changing results, but in addition have amassed large quantities of clinical data and patient samples which hold huge potential to help the research community investigate a number of unanswered questions. In addition, organisations such as Biobank UK and UK Clinical Research Collaboration have developed valuable resources to help researchers access patient data and samples to investigate the prevention, diagnosis and treatment of a wide range of serious and life-threatening illnesses.

If the data and samples amassed through these clinical trials and other initiatives could be used to answer those questions, we may be able to significantly and quickly improve the way prostate cancer is diagnosed and treated.

On 5 August 2019, we launched a funding call for proposals looking to utilise and interrogate existing patient samples and/or data from recently completed or ongoing prostate cancer clinical trials, or from other data/sample repositories.

The specific remit for this call is detailed in the corresponding guidance notes

The submission deadline is 12pm (noon) Monday 14 October 2019

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Remit & Eligibility

Proposals must seek to answer new and innovative questions, which if addressed, could make a significant impact in the way prostate cancer is diagnosed or treated. This could be the in-depth analysis of trial databases, repositories of patient data, images and/or patient samples, to investigate new hypotheses that could, for instance, help identify responders/non-responders to particular therapies, or to discover biomarkers which may more accurately distinguish aggressive cancer from indolent disease etc.

Proposals must have a strong central hypothesis. Applications that are not hypothesis-driven and which are seeking to only collect or curate patient samples/trial data will not be accepted.

In order to be within the remit of this funding call, your application must:

  • Be led through a UK based academic institution (international collaborations are encouraged)
  • Align with our research strategy; better diagnosis, better treatment and better prevention
  • Be hypothesis driven, clearly outlining the new question(s) that this specific grant will aim to answer
  • Identify appropriate existing datasets, images or patient samples to answer an innovative question that may impact the way prostate cancer is diagnosed or treated
  • Have written agreed access to the data, samples or images from the relevant parties at the point of application.

Applications intending to utilise/interrogate datasets, samples or images from international and/or industry partners are eligible and encouraged. However, proposals must be led by an individual(s) based at a UK academic institution (please refer the guidance document for further details).

Researchers with proposals which are not within remit for this call but which are innovative and address one or more of the areas outlined within our research strategy should consider applying to our Research Innovation Awards Scheme.

Application Process

Applications must be made by the Principal Investigator using our online Grant Management System.  The funding call will consist of a single application stage.

  • Submission deadline in 12pm noon on Monday 14 October 2019.
  • Applications received will first be validated by the Research Team at Prostate Cancer UK to ensure that they meet the basic eligibility criteria for this call. Proposals which do not meet the scope of this call will be rejected.
  • Applications will then be peer reviewed by at least three independent referees (in accordance with AMRC guidelines).
  • Rebuttals of peer reviewer comments must be submitted  by 20 January 2020.
  • Following peer review, proposals will be assessed by representatives of our Research Advisory Committee and co-opted members with particular expertise needed to assess applications to this call.  
  • Final funding decisions will be made before the end of March 2020. All awards are subject to our standard terms and conditions. Please note that these terms are subject to change.

Contact us

If you have any queries regarding this call, please contact the Research Team at Prostate Cancer UK via research@prostatecanceruk.org