This fact sheet is for men who have been offered radiotherapy to treat prostate cancer that has spread from the prostate to other parts of the body (advanced prostate

Last updated: March 2019
To be reviewed: June 2021


  • Bashir FA, Parry JM & Windsor PM. Use of a modified hemi-body irradiation technique for metastatic carcinoma of the prostate: Report of a 10-year experience. Clinical Oncology. 2008;20:591-598
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  • GE Healthcare. Metastron (Strontium-89 chloride injection). 2006
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  • Li KK, Hadi S, Kirou-Mauro A et al. When should we define the response rates in the treatment of bone metastases by palliative radiotherapy? Clinical Oncology (Royal College of Radiologists). 2008;20(1):83-9
  • Loblaw DA, Wu JS, Jackson S, Kirkbride P. Pain flare in patients with bone metastases after palliative radiotherapy--a nested randomized control trial. Supportive Care in Cancer. 2007;15(4):451-5
  • Lutz S, Berk L, Chang E, et al. Palliative radiotherapy for bone metastases: An ASTRO evidence-based guideline. Int. J. Radiation Oncology Biol. Phys. 2011;79
  • National Institute for Health and Clinical Excellence, Prostate Cancer: diagnosis and treatment (Full guidance). February 2008
  • Notes for Guidance on the Clinical Administration of Radiopharmaceuticals and Use of Sealed Radioactive Sources. Administration of Radioactive Substances Advisory Committee 2006. Revised 2011.
  • Oosterhof GON, Roberts JT, de Reijke Th.M, et al. Strontium89 Chloride versus Palliative Local Field Radiotherapy in Patients with Hormonal Escaped Prostate Cancer: A Phase II Studyof the European Organisation for Research andTreatment of Cancer Genitourinary Group. European Urology. 44 (2003) 519–526
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